Peptide Database

Peptide NameiAβ5p-C2

Function Ontology

beta-sheet breaker peptides

Standard StatusStandard

Sequence Length5 amino acids

Chemical FormulaC23H42N8O7

DescriptionStandard

        SARLP
    

Molecular Weight542.63 Da

Isoelectric Point (pI)9.47

Net Charge (pH 7.0)0.46

Net Charge (pH 7.4) 0.25

Charge Density (pH 7.0) 0.0920

GRAVY Index-0.26

Hydrophobic Moment 0.56

Boman Index-0.18

Instability Index46.52

Aliphatic Index 98.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 253.06

LogP -2.83

H-bond Donors 9.0

H-bond Acceptors 8.0

Rotatable Bonds 15.0

Heavy Atoms 38.0

Ring Count 1.0

Amide Bonds 4.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0288853 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyAmyloid-beta

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermSar

C-TermAmidation

Bio-Activity Profile

Function

beta-sheet breaker peptides

MethodRP-HPLC

Half-LifeRat brain homogenate, in vitro; 2460 s