Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length196 amino acids

Chemical FormulaC989H1564N266O264S10

DescriptionStandard

        PKTLPMAHEPMLLVAVTELVANSAAFTYFTAGALRRNLSSDMLPRQFPLQLRTKSMEVFSPELQERYPDQPMELHLWARQQPLLSCHPDALHGTLFSSAEAFVVLPNATRVPAFLLNIDANVTGKPTIARNRLGGTVRLTGLVPNPELAWTPLPALCWAQDPPIPQVKRLETLLKFGLWLFGVPRAKSKCCPCPVP
    

Molecular Weight21725.27 Da

Isoelectric Point (pI)9.17

Net Charge (pH 7.0)5.28

Net Charge (pH 7.4) 4.91

Charge Density (pH 7.0) 0.0269

GRAVY Index0.02

Hydrophobic Moment 0.55

Boman Index0.10

Instability Index50.98

Aliphatic Index 94.59

Aromaticity 0.0765

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8278.55

LogP -98.29

H-bond Donors 283.0

H-bond Acceptors 283.0

Rotatable Bonds 678.0

Heavy Atoms 1529.0

Ring Count 47.0

Amide Bonds 210.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0389992 VERIFIED: NO

Provenance & Taxonomy

OrganismZosterops hypoxanthus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria