Peptide Database

Peptide NameFamily with sequence similarity 193 member A [0146-0152]

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC34H61N11O10

DescriptionStandard

        LRPKAAE
    

Molecular Weight783.92 Da

Isoelectric Point (pI)8.75

Net Charge (pH 7.0)0.77

Net Charge (pH 7.4) 0.56

Charge Density (pH 7.0) 0.1096

GRAVY Index-0.87

Hydrophobic Moment 0.15

Boman Index-0.34

Instability Index63.60

Aliphatic Index 84.29

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 354.35

LogP -2.84

H-bond Donors 12.0

H-bond Acceptors 11.0

Rotatable Bonds 25.0

Heavy Atoms 55.0

Ring Count 1.0

Amide Bonds 6.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0054244 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory ACE inhibitory

TargetAngiotensin-converting enzyme

Activity26.1 ± 3.69 μM

MethodIC50