Peptide Database

Peptide NameSLAY-screened peptide P3202

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC88H149N29O32S3

DescriptionStandard

        PNCYAMRTTRNSTSSKSCTL
    

Molecular Weight2221.49 Da

Isoelectric Point (pI)9.53

Net Charge (pH 7.0)2.94

Net Charge (pH 7.4) 2.85

Charge Density (pH 7.0) 0.1468

GRAVY Index-0.81

Hydrophobic Moment 0.47

Boman Index-0.29

Instability Index64.53

Aliphatic Index 24.50

Aromaticity 0.0500

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1020.30

LogP -17.44

H-bond Donors 41.0

H-bond Acceptors 38.0

Rotatable Bonds 72.0

Heavy Atoms 152.0

Ring Count 2.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0073081 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/