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MYP_000193
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Basic Information
Substance P
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Tachykinin peptide
Standard
8 amino acids
C43H69N13O11S
Standard
Sequence
RPQQFGLM
Physicochemical Analysis
976.15 Da
9.75
0.76
0.56
0.0950
-0.62
0.24
-0.09
71.55
48.75
0.1250
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
406.31
-3.23
13.0
13.0
31.0
68.0
2.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0131852 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Tachykinin
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Tachykinin Neuropeptide Neuromodulator
PMID504332 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/504332/
RECORD: Rec_0140154 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0401710 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Substance P
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide Neuromodulator
Mammalian: 1 hour; Yeast: 2 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Substance P (Rattus norvegicus): PMID 504332 PMID504332 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/504332/