Peptide Database

Peptide NameBrevinin-1CG4

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length71 amino acids

Chemical FormulaC366H606N98O110S4

DescriptionStandard

        MFTLKKSLLLLFFLGTINLSLCEQERNADEEERRDDSDKRDVEVEKRFLSTLLNVASKVVPTLFCKITKKC
    

Molecular Weight8267.58 Da

Isoelectric Point (pI)7.68

Net Charge (pH 7.0)0.49

Net Charge (pH 7.4) 0.20

Charge Density (pH 7.0) 0.0069

GRAVY Index-0.23

Hydrophobic Moment 0.64

Boman Index-0.12

Instability Index41.71

Aliphatic Index 100.14

Aromaticity 0.0704

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3431.45

LogP -30.27

H-bond Donors 123.0

H-bond Acceptors 115.0

Rotatable Bonds 291.0

Heavy Atoms 578.0

Ring Count 6.0

Amide Bonds 74.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0378315 VERIFIED: NO

Provenance & Taxonomy

OrganismAmolops chunganensis [Animal]

FamilyFrog skin active peptide (FSAP)

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antibiotic Antimicrobial Antifungal Fungicide Anti-Candida Cytolytic Hemolytic Non-ribosomal

TargetCandida albicans

MethodQualitative functional evidence