Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length69 amino acids

Chemical FormulaC349H568N90O87S7

DescriptionStandard

        MKPFLLTLAVLLLLSQVIPGSAEKCWNLHGTCRGKCGKNEKFFLFCKSGKLCCLKLNFQPNLPLKSLSA
    

Molecular Weight7641.25 Da

Isoelectric Point (pI)9.54

Net Charge (pH 7.0)7.52

Net Charge (pH 7.4) 7.15

Charge Density (pH 7.0) 0.1091

GRAVY Index0.30

Hydrophobic Moment 0.37

Boman Index0.14

Instability Index11.67

Aliphatic Index 103.19

Aromaticity 0.0870

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2822.26

LogP -21.20

H-bond Donors 101.0

H-bond Acceptors 103.0

Rotatable Bonds 257.0

Heavy Atoms 533.0

Ring Count 12.0

Amide Bonds 74.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0280383 VERIFIED: NO

Provenance & Taxonomy

OrganismEquus caballus [Animal]

FamilyDefensin

Tax ID9796

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence