Peptide Database

Peptide NameInterleukin-11

Function Ontology

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length178 amino acids

Chemical FormulaC859H1418N254O236S2

DescriptionStandard

        PGPPPGPPRVSPDPRAELDSTVLLTRSLLADTRQLAAQLRDKFPADGDHNLDSLPTLAMSAGALGALQLPGVLTRLRADLLSYLRHVQWLRRAGGSSLKTLEPELGTLQARLDRLLRRLQLLMSRLALPQPPPDPPAPPLAPPSSAWGGIRAAHAILGGLHLTLDWAVRGLLLLKTRL
    

Molecular Weight19144.14 Da

Isoelectric Point (pI)11.16

Net Charge (pH 7.0)7.32

Net Charge (pH 7.4) 7.05

Charge Density (pH 7.0) 0.0411

GRAVY Index-0.08

Hydrophobic Moment 0.82

Boman Index0.03

Instability Index62.42

Aliphatic Index 113.60

Aromaticity 0.0281

Extinction Coeff. Reduced 17990.00

Extinction Coeff. Oxidized 17990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7661.54

LogP -85.74

H-bond Donors 265.0

H-bond Acceptors 249.0

Rotatable Bonds 607.0

Heavy Atoms 1351.0

Ring Count 34.0

Amide Bonds 185.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0056391 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyIL-6 superfamily

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Cytokine Growth factor IL-6 superfamily Growth factor signaling