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MYP_000104
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Basic Information
Temporin-1Cc
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
13 amino acids
C74H120N14O16
Standard
Sequence
FLPFLASLLTKVL
Physicochemical Analysis
1461.83 Da
8.75
0.76
0.55
0.0584
1.82
0.42
0.60
32.33
180.00
0.1538
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
470.21
0.62
16.0
17.0
45.0
104.0
3.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0251371 VERIFIED: YES
Provenance & Taxonomy
Rana clamitans [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
No MICs found in DRAMP database
PMID10822101 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10822101/
RECORD: Rec_0254766 VERIFIED: YES
Provenance & Taxonomy
Lithobates clamitans [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-positive Non-hemolytic
Gram-positive bacteria
PMID10822101 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10822101/
RECORD: Rec_0307795 VERIFIED: YES
Provenance & Taxonomy
Lithobates calamitans [Animal]
Temporin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
PaperT. Halverson et al. / Peptides 21 (2000) 469-476. Purification and characterization of antimicrobial peptides from the skin of the North American green frog Rana clamitans Evidence URLhttps://www.uniprot.org/uniprotkb/P82882/entry
RECORD: Rec_0330477 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0358646 VERIFIED: NO
Provenance & Taxonomy
Rana clamitans [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial
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