Peptide Database

Peptide NamePeptide 6

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-Coronavirus ▸ Anti-SARS-CoV-2

Antiviral ▸ Anti-Herpesvirus ▸ Anti-HCMV

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition

Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Standard StatusStandard

Sequence Length4 amino acids

Chemical FormulaC18H34N4O5

DescriptionStandard

        GVLV
    

Molecular Weight386.49 Da

Isoelectric Point (pI)5.53

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.44

Charge Density (pH 7.0) -0.0600

GRAVY Index2.95

Hydrophobic Moment 0.07

Boman Index0.93

Instability Index7.50

Aliphatic Index 242.50

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 150.62

LogP -0.16

H-bond Donors 5.0

H-bond Acceptors 5.0

Rotatable Bonds 11.0

Heavy Atoms 27.0

Ring Count 0.0

Amide Bonds 3.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0279608 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAc

Other ModsAcylation; Methyl amidation

Bio-Activity Profile

Function

Antiviral

Targethuman cytomegalovirus

Activity4 μM

MethodEC50

RECORD: Rec_0315763 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAc

Other ModsAcylation; Methyl amidation

Bio-Activity Profile

Function

Antiviral

Targetvaricella-zoster virus ATCC VR-795

Activity20 μM

MethodEC50

RECORD: Rec_0386990 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAc

Other ModsAcylation; Methyl amidation

Bio-Activity Profile

Function

Antiviral

Targetthymidine kinase deficient

Activity20 μM

MethodEC50

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