Peptide Database

Peptide NameLysozyme (EC 3.2.1.17)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length177 amino acids

Chemical FormulaC854H1360N254O250S10

DescriptionStandard

        MNAKIRYGLSAAVLALIGAGASAPEILDQFLDEKEGNHTTAYRDGTGIWTICRGAILVDGKPVVPGMKLSKEKCDQVNAIERDKALAWVEKNIKVPLTDPQKAGIASFCPYNIGPGKCFPSTFYRRINAGDRRGACEAIRWWIKDGGRDCRIRSNNCYGQVSRRDQESALACWGIDR
    

Molecular Weight19506.14 Da

Isoelectric Point (pI)9.06

Net Charge (pH 7.0)6.53

Net Charge (pH 7.4) 6.10

Charge Density (pH 7.0) 0.0369

GRAVY Index-0.37

Hydrophobic Moment 0.72

Boman Index-0.06

Instability Index40.86

Aliphatic Index 78.93

Aromaticity 0.0791

Extinction Coeff. Reduced 34950.00

Extinction Coeff. Oxidized 35450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8153.51

LogP -87.37

H-bond Donors 293.0

H-bond Acceptors 268.0

Rotatable Bonds 648.0

Heavy Atoms 1368.0

Ring Count 28.0

Amide Bonds 189.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0013924 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyLysozyme

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase

RECORD: Rec_0053452 VERIFIED: YES

Provenance & Taxonomy

OrganismEnterobacteria phage H19B [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Cytolytic Non-hemolytic

RECORD: Rec_0380550 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli 97.0246 [Bacterium]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic Non-ribosomal

MethodQualitative functional evidence