Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC550H876N146O169S4

DescriptionStandard

        PDLSGYEKFGLGNVKYNISRIHVTAVEFPSASISLIPGTGIKLVIGNASLTIDMNWNIRTWMFKDSGRSTVYISKVFVTAIFSTSLDNTGHTSMSLTSCRTTSGDIDIKLNGKS
    

Molecular Weight12365.98 Da

Isoelectric Point (pI)9.24

Net Charge (pH 7.0)3.13

Net Charge (pH 7.4) 2.93

Charge Density (pH 7.0) 0.0274

GRAVY Index0.03

Hydrophobic Moment 0.53

Boman Index0.12

Instability Index19.26

Aliphatic Index 89.74

Aromaticity 0.0877

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5065.89

LogP -57.74

H-bond Donors 183.0

H-bond Acceptors 178.0

Rotatable Bonds 410.0

Heavy Atoms 869.0

Ring Count 17.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0096261 VERIFIED: NO

Provenance & Taxonomy

OrganismCentropus unirufus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria