Peptide Database

Peptide NameConopressin-T

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC47H78N14O13S2

DescriptionStandard

        CYIQNCLRV
    

Molecular Weight1111.34 Da

Isoelectric Point (pI)8.06

Net Charge (pH 7.0)0.74

Net Charge (pH 7.4) 0.51

Charge Density (pH 7.0) 0.0821

GRAVY Index0.52

Hydrophobic Moment 0.57

Boman Index0.02

Instability Index48.49

Aliphatic Index 118.89

Aromaticity 0.1111

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 464.43

LogP -3.76

H-bond Donors 18.0

H-bond Acceptors 16.0

Rotatable Bonds 35.0

Heavy Atoms 76.0

Ring Count 1.0

Amide Bonds 10.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0071440 VERIFIED: YES

Provenance & Taxonomy

OrganismConus tulipa [Animal]

Structure & Mods

Configdisulfide-constrained peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide1-6

Bio-Activity Profile

Function

Hormone

Targethuman V1a receptor

Methodreceptor antagonism assay

RECORD: Rec_0166304 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 0.0%, E 0.0%, T 22.2%, C 77.8% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Miscellaneous

RECORD: Rec_0203591 VERIFIED: YES

Provenance & Taxonomy

OrganismConus tulipa [Animal]

FamilyConopressin-T

Tax ID6495

Structure & Mods

Configdisulfide-constrained peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide1-6

Bio-Activity Profile

Function

Hormone Endocrine Receptor modulation

Targethuman V1a receptor

Activity10 μM

Methodreceptor antagonism assay

Half-LifeMammalian: 1.2 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0210663 VERIFIED: YES

Provenance & Taxonomy

OrganismConus tulipa [Animal]

FamilyConopressin-T

Tax ID6495

Structure & Mods

Configdisulfide-constrained peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide1-6

Bio-Activity Profile

Function

Hormone Endocrine Receptor modulation

TargetV1a receptor

Activity0.108 μM

MethodKi

Half-LifeMammalian: 1.2 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0317261 VERIFIED: YES

Provenance & Taxonomy

OrganismConus tulipa [Animal]

FamilyConopressin-T

Tax ID6495

Structure & Mods

Configdisulfide-constrained peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide1-6

Bio-Activity Profile

Function

Hormone Endocrine Receptor modulation

TargetV1b and V2 receptors

Methodreceptor binding/functional selectivity assay

Half-LifeMammalian: 1.2 hour; Yeast: >20 hour; E. coli: >10 hour