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NO. RECORD ID NAME SEQUENCE SOURCE ORGANISM FUNCTION CATEGORY TARGET ORGANISM ACTIVITY ASSAY METHOD PMID PATENT NO VERIFICATION STATUS
421701 Rec_0434359
LRR5M
LGTNPLKSSGIE
synthetic construct [Synthetic]
-
Homo sapiens (human umbilical vein endothelial cells, HUVECs)
0.24 absorbance at 460 nm
EZ4U cytotoxicity assessment (absorbance at 460 nm, 6 h)
15923192
-
YES
421702 Rec_0434360
LRR5M
LGTNPLKSSGIE
synthetic construct [Synthetic]
-
Homo sapiens (human umbilical vein endothelial cells, HUVECs)
0.21 absorbance at 460 nm
EZ4U cytotoxicity assessment (absorbance at 460 nm, 6 h)
15923192
-
YES
421703 Rec_0434361
LRR5C
SSGIENGAFQGMK
synthetic construct [Synthetic]
-
Homo sapiens (human umbilical vein endothelial cells, HUVECs)
0.25 absorbance at 460 nm
EZ4U cytotoxicity assessment (absorbance at 460 nm, 6 h)
15923192
-
YES
421704 Rec_0434362
LRR5C
SSGIENGAFQGMK
synthetic construct [Synthetic]
-
Homo sapiens (human umbilical vein endothelial cells, HUVECs)
0.26 absorbance at 460 nm
EZ4U cytotoxicity assessment (absorbance at 460 nm, 6 h)
15923192
-
YES
421705 Rec_0434363
LRR5C
SSGIENGAFQGMK
synthetic construct [Synthetic]
-
Homo sapiens (human umbilical vein endothelial cells, HUVECs)
0.27 absorbance at 460 nm
EZ4U cytotoxicity assessment (absorbance at 460 nm, 6 h)
15923192
-
YES
421706 Rec_0434364
LRR5C
SSGIENGAFQGMK
synthetic construct [Synthetic]
-
Homo sapiens (human umbilical vein endothelial cells, HUVECs)
0.26 absorbance at 460 nm
EZ4U cytotoxicity assessment (absorbance at 460 nm, 6 h)
15923192
-
YES
421707 Rec_0434365
LRR5C
SSGIENGAFQGMK
synthetic construct [Synthetic]
-
Homo sapiens (human umbilical vein endothelial cells, HUVECs)
0.25 absorbance at 460 nm
EZ4U cytotoxicity assessment (absorbance at 460 nm, 6 h)
15923192
-
YES
421708 Rec_0434366
LRR5 (FITC-labeled)
QMIVIELGTNPLKSSGIENGAFQGMK
synthetic construct [Synthetic]
-
Collagen I
27 ± 8.7 μM
Kd (FITC-peptide solid-phase binding, single-site nonlinear regression)
15923192
-
YES
421709 Rec_0434367
LRR5N (FITC-labeled)
QMIVIELGTNPLK
synthetic construct [Synthetic]
-
Collagen I
45 ± 19.7 μM
Kd (FITC-peptide solid-phase binding, single-site nonlinear regression)
15923192
-
YES
421710 Rec_0434368
LRR5M (FITC-labeled)
LGTNPLKSSGIE
synthetic construct [Synthetic]
-
Collagen I
58 ± 12.8 μM
Kd (FITC-peptide solid-phase binding, single-site nonlinear regression)
15923192
-
YES
421711 Rec_0434369
LRR5C (FITC-labeled)
SSGIENGAFQGMK
synthetic construct [Synthetic]
-
Collagen I
308 ± 58.5 μM
Kd (FITC-peptide solid-phase binding, single-site nonlinear regression)
15923192
-
YES
421712 Rec_0434370
LRR5 (FITC-labeled)
QMIVIELGTNPLKSSGIENGAFQGMK
synthetic construct [Synthetic]
-
Fibronectin
808 ± 223.5 μM
Kd (FITC-peptide solid-phase binding, single-site nonlinear regression)
15923192
-
YES
421713 Rec_0434371
LRR5N (FITC-labeled)
QMIVIELGTNPLK
synthetic construct [Synthetic]
-
Fibronectin
5140 ± 272.0 μM
Kd (FITC-peptide solid-phase binding, single-site nonlinear regression)
15923192
-
YES
421714 Rec_0434372
LRR5M (FITC-labeled)
LGTNPLKSSGIE
synthetic construct [Synthetic]
-
Fibronectin
1400 ± 268.9 μM
Kd (FITC-peptide solid-phase binding, single-site nonlinear regression)
15923192
-
YES
421715 Rec_0434373
LRR5C (FITC-labeled)
SSGIENGAFQGMK
synthetic construct [Synthetic]
-
Fibronectin
2760 ± 132.7 μM
Kd (FITC-peptide solid-phase binding, single-site nonlinear regression)
15923192
-
YES
421716 Rec_0434374
LRR5
QMIVIELGTNPLKSSGIENGAFQGMK
synthetic construct [Synthetic]
Anti-angiogenic
Homo sapiens (human umbilical vein endothelial cells, HUVECs)
~100 nM
Estimated ED50 (VEGF-induced HUVEC tube formation on Matrigel, 4-6 h)
15923192
-
YES
421717 Rec_0434375
LRR5
QMIVIELGTNPLKSSGIENGAFQGMK
synthetic construct [Synthetic]
Anti-angiogenic
Homo sapiens (human umbilical vein endothelial cells, HUVECs)
-
HUVEC tube formation on Matrigel (bFGF, 4-6 h)
15923192
-
YES
421718 Rec_0434376
LRR5N
QMIVIELGTNPLK
synthetic construct [Synthetic]
-
Homo sapiens (human umbilical vein endothelial cells, HUVECs)
-
HUVEC tube formation on Matrigel (VEGF, 4-6 h)
15923192
-
YES
421719 Rec_0434377
LRR5N
QMIVIELGTNPLK
synthetic construct [Synthetic]
Anti-angiogenic
Homo sapiens (human umbilical vein endothelial cells, HUVECs)
-
HUVEC tube formation on Matrigel (bFGF, 4-6 h)
15923192
-
YES
421720 Rec_0434378
LRR5M
LGTNPLKSSGIE
synthetic construct [Synthetic]
Anti-angiogenic
Homo sapiens (human umbilical vein endothelial cells, HUVECs)
~100 pM
Estimated ED50 (VEGF-induced HUVEC tube formation on Matrigel, 4-6 h)
15923192
-
YES
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