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NO. RECORD ID NAME SEQUENCE SOURCE ORGANISM FUNCTION CATEGORY TARGET ORGANISM ACTIVITY ASSAY METHOD PMID PATENT NO VERIFICATION STATUS
421641 Rec_0434299
Pentastatin-1
LRRFSTMPFMFCNINNVCNF
synthetic construct [Synthetic]
Anticancer
NCI-H82 xenografts in athymic nude mice
44 % inhibition
Tumor xenograft growth inhibition (caliper measurements)
20122172
-
YES
421642 Rec_0434300
Pentastatin-1
LRRFSTMPFMFCNINNVCNF
synthetic construct [Synthetic]
Anticancer
NCI-H82 xenografts in athymic nude mice
59 % inhibition
Tumor xenograft growth inhibition (caliper measurements)
20122172
-
YES
421643 Rec_0434301
Pentastatin-1
LRRFSTMPFMFCNINNVCNF
synthetic construct [Synthetic]
Anticancer
NCI-H82 xenografts in athymic nude mice
49 % inhibition
Tumor xenograft growth inhibition (caliper measurements)
20122172
-
YES
421644 Rec_0434302
Pentastatin-1
LRRFSTMPFMFCNINNVCNF
synthetic construct [Synthetic]
Anticancer
NCI-H82 xenografts in athymic nude mice
53 % inhibition
Tumor xenograft growth inhibition (caliper measurements)
20122172
-
YES
421645 Rec_0434303
Pentastatin-1
LRRFSTMPFMFCNINNVCNF
synthetic construct [Synthetic]
Anti-angiogenic
NCI-H82 xenograft sections in athymic nude mice
23 % decrease
CD31 immunohistochemical microvascular-density assay
20122172
-
YES
421646 Rec_0434304
Pentastatin-1
LRRFSTMPFMFCNINNVCNF
synthetic construct [Synthetic]
Anti-angiogenic
NCI-H82 xenograft sections in athymic nude mice
24 % decrease
CD31 immunohistochemical microvascular-density assay
20122172
-
YES
421647 Rec_0434305
Pentastatin-1
LRRFSTMPFMFCNINNVCNF
synthetic construct [Synthetic]
-
NCI-H82 xenograft microenvironment in athymic nude mice
19 cells/frame
Cleaved caspase-3 immunohistochemistry
20122172
-
YES
421648 Rec_0434306
Pentastatin-1
LRRFSTMPFMFCNINNVCNF
synthetic construct [Synthetic]
-
NCI-H82 xenograft microenvironment in athymic nude mice
22 cells/frame
Cleaved caspase-3 immunohistochemistry
20122172
-
YES
421649 Rec_0434307
FSEN
CQNHHAKHGKVC
synthetic construct [Synthetic]
Anti-angiogenic
Matrigel plug sections in athymic nude mice
-
Matrigel plug angiogenesis assay (SMA immunofluorescent area)
20525313
-
YES
421650 Rec_0434308
FSEC
CELDENNTPMC
synthetic construct [Synthetic]
Anti-angiogenic
Matrigel plug sections in athymic nude mice
-
Matrigel plug angiogenesis assay (SMA immunofluorescent area)
20525313
-
YES
421651 Rec_0434309
scFSEN
KCGHKHQCAVHN
synthetic construct [Synthetic]
Control peptide
Matrigel plug sections in athymic nude mice
-
Matrigel plug angiogenesis assay (SMA immunofluorescent area)
20525313
-
YES
421652 Rec_0434310
scFSEC
MEPECNLNCTD
synthetic construct [Synthetic]
Control peptide
Matrigel plug sections in athymic nude mice
-
Matrigel plug angiogenesis assay (SMA immunofluorescent area)
20525313
-
YES
421653 Rec_0434311
FSEN
CQNHHAKHGKVC
synthetic construct [Synthetic]
-
Matrigel plug sections in athymic nude mice
-
Matrigel plug pericyte-to-endothelial area ratio
20525313
-
YES
421654 Rec_0434312
FSEN
CQNHHAKHGKVC
synthetic construct [Synthetic]
-
HUVEC (bFGF-stimulated proliferation)
-
CellTiter HUVEC proliferation assay
20525313
-
YES
421655 Rec_0434313
FSEC
CELDENNTPMC
synthetic construct [Synthetic]
-
Matrigel plug sections in athymic nude mice
-
Matrigel plug pericyte-to-endothelial area ratio
20525313
-
YES
421656 Rec_0434314
FSEC
CELDENNTPMC
synthetic construct [Synthetic]
-
HUVEC (bFGF-stimulated proliferation)
-
CellTiter HUVEC proliferation assay
20525313
-
YES
421657 Rec_0434315
FSEN
CQNHHAKHGKVC
synthetic construct [Synthetic]
Anti-angiogenic
SMS-KCNR neuroblastoma xenografts in athymic nude mice
15.0 ± 4.0 10^3 pixels
CD31 immunofluorescent area quantification
20525313
-
YES
421658 Rec_0434316
FSEN
CQNHHAKHGKVC
synthetic construct [Synthetic]
Anti-angiogenic
SMS-KCNR neuroblastoma xenografts in athymic nude mice
12.8 ± 6.2 10^3 pixels
SMA immunofluorescent area quantification
20525313
-
YES
421659 Rec_0434317
FSEC
CELDENNTPMC
synthetic construct [Synthetic]
Anti-angiogenic
SMS-KCNR neuroblastoma xenografts in athymic nude mice
5.9 ± 2.6 10^3 pixels
CD31 immunofluorescent area quantification
20525313
-
YES
421660 Rec_0434318
FSEC
CELDENNTPMC
synthetic construct [Synthetic]
Anti-angiogenic
SMS-KCNR neuroblastoma xenografts in athymic nude mice
6.2 ± 4.0 10^3 pixels
SMA immunofluorescent area quantification
20525313
-
YES
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