ASSAY RECORD
Results
Showing up to 20 records.
| NO. | RECORD ID | NAME | SEQUENCE | SOURCE ORGANISM | FUNCTION CATEGORY | TARGET ORGANISM | ACTIVITY | ASSAY METHOD | PMID | PATENT NO | VERIFICATION STATUS |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 421621 | Rec_0434279 | TIMP-3 Loop 5 |
KIKSCYYLPCFVTS |
Homo sapiens [Animal] |
- |
PAE/KDR cells (porcine aortic endothelial cells expressing VEGFR-2) |
- | Actin reorganization assay (FITC-phalloidin fluorescence microscopy) |
23469166 | - |
YES |
| 421622 | Rec_0434280 | TIMP-3 Loop 5 |
KIKSCYYLPCFVTS |
Homo sapiens [Animal] |
- |
PAE/KDR cells (porcine aortic endothelial cells expressing VEGFR-2) |
- | Endothelial proliferation assay (Coulter particle counting) |
23469166 | - |
YES |
| 421623 | Rec_0434281 | TIMP-3 Loop 6 |
KNECLWTDMLSNFGYPGYQSKHYACIRQKG |
Homo sapiens [Animal] |
Anti-angiogenic |
PAE/KDR cells (porcine aortic endothelial cells expressing VEGFR-2) |
- | Endothelial proliferation assay (Coulter particle counting) |
23469166 | - |
YES |
| 421624 | Rec_0434282 | TIMP-3 Tail |
GYCSWYRGWAPPDKSIINATDP |
Homo sapiens [Animal] |
Anti-angiogenic |
PAE/KDR cells (porcine aortic endothelial cells expressing VEGFR-2) |
- | Endothelial proliferation assay (Coulter particle counting) |
23469166 | - |
YES |
| 421625 | Rec_0434283 | TIMP-3 Tail |
GYCSWYRGWAPPDKSIINATDP |
Homo sapiens [Animal] |
Anti-angiogenic |
C57BL/6 mice (laser-induced choroidal neovascularization) |
- | Laser-induced CNV lesion assay (fluorescein angiography/scanning laser ophthalmoscopy) |
23469166 | - |
YES |
| 421626 | Rec_0434284 | TIMP-3 Tail |
GYCSWYRGWAPPDKSIINATDP |
Homo sapiens [Animal] |
Anti-angiogenic |
C57BL/6 mice (laser-induced choroidal neovascularization) |
- | Laser-induced CNV lesion assay (fluorescein angiography/scanning laser ophthalmoscopy) |
23469166 | - |
YES |
| 421627 | Rec_0434285 | TIMP-3 Tail |
GYCSWYRGWAPPDKSIINATDP |
Homo sapiens [Animal] |
- |
C57BL/6 mice (laser-induced choroidal neovascularization) |
- | Laser-induced CNV lesion assay (fluorescein angiography/scanning laser ophthalmoscopy) |
23469166 | - |
YES |
| 421628 | Rec_0434286 | Pentastatin-1 |
LRRFSTMPFMFCNINNVCNF |
synthetic construct [Synthetic] |
Anticancer |
NCI-H82 human small-cell lung cancer cells |
26 % decrease | WST-1 cell viability assay |
20122172 | - |
YES |
| 421629 | Rec_0434287 | Pentastatin-1 |
LRRFSTMPFMFCNINNVCNF |
synthetic construct [Synthetic] |
Anticancer |
NCI-H82 human small-cell lung cancer cells |
42 % decrease | WST-1 cell viability assay |
20122172 | - |
YES |
| 421630 | Rec_0434288 | Pentastatin-1 |
LRRFSTMPFMFCNINNVCNF |
synthetic construct [Synthetic] |
- |
3T3 mouse fibroblasts |
20 % decrease | WST-1 cell viability assay |
20122172 | - |
YES |
| 421631 | Rec_0434289 | Pentastatin-1 |
LRRFSTMPFMFCNINNVCNF |
synthetic construct [Synthetic] |
- |
3T3 mouse fibroblasts |
81 % decrease | WST-1 cell viability assay |
20122172 | - |
YES |
| 421632 | Rec_0434290 | Pentastatin-1 |
LRRFSTMPFMFCNINNVCNF |
synthetic construct [Synthetic] |
Anticancer |
NCI-H82 human small-cell lung cancer cells |
50 % inhibition | BrdU incorporation assay |
20122172 | - |
YES |
| 421633 | Rec_0434291 | Pentastatin-1 |
LRRFSTMPFMFCNINNVCNF |
synthetic construct [Synthetic] |
- |
3T3 mouse fibroblasts |
33 % inhibition | BrdU incorporation assay |
20122172 | - |
YES |
| 421634 | Rec_0434292 | Pentastatin-1 |
LRRFSTMPFMFCNINNVCNF |
synthetic construct [Synthetic] |
Anti-angiogenic |
C57BL/6 mice (angioreactor vascularization) |
19 % decrease | Directed in vivo angiogenesis assay (DIVAA) |
20122172 | - |
YES |
| 421635 | Rec_0434293 | Pentastatin-1 |
LRRFSTMPFMFCNINNVCNF |
synthetic construct [Synthetic] |
Anti-angiogenic |
C57BL/6 mice (angioreactor vascularization) |
67 % decrease | Directed in vivo angiogenesis assay (DIVAA) |
20122172 | - |
YES |
| 421636 | Rec_0434294 | Pentastatin-1 |
LRRFSTMPFMFCNINNVCNF |
synthetic construct [Synthetic] |
Anti-angiogenic |
C57BL/6 mice (angioreactor vascularization) |
88 % decrease | Directed in vivo angiogenesis assay (DIVAA) |
20122172 | - |
YES |
| 421637 | Rec_0434295 | Pentastatin-1 |
LRRFSTMPFMFCNINNVCNF |
synthetic construct [Synthetic] |
Anticancer |
NCI-H82 xenografts in athymic nude mice |
27 % inhibition | Tumor xenograft growth inhibition (caliper measurements) |
20122172 | - |
YES |
| 421638 | Rec_0434296 | Pentastatin-1 |
LRRFSTMPFMFCNINNVCNF |
synthetic construct [Synthetic] |
Anticancer |
NCI-H82 xenografts in athymic nude mice |
36 % inhibition | Tumor xenograft growth inhibition (caliper measurements) |
20122172 | - |
YES |
| 421639 | Rec_0434297 | Pentastatin-1 |
LRRFSTMPFMFCNINNVCNF |
synthetic construct [Synthetic] |
Anticancer |
NCI-H82 xenografts in athymic nude mice |
20 % inhibition | Tumor xenograft growth inhibition (caliper measurements) |
20122172 | - |
YES |
| 421640 | Rec_0434298 | Pentastatin-1 |
LRRFSTMPFMFCNINNVCNF |
synthetic construct [Synthetic] |
Anticancer |
NCI-H82 xenografts in athymic nude mice |
20 % inhibition | Tumor xenograft growth inhibition (caliper measurements) |
20122172 | - |
YES |