ASSAY RECORD
Results
Showing up to 20 records.
| NO. | RECORD ID | NAME | SEQUENCE | SOURCE ORGANISM | FUNCTION CATEGORY | TARGET ORGANISM | ACTIVITY | ASSAY METHOD | PMID | PATENT NO | VERIFICATION STATUS |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 420541 | Rec_0433199 | α-Conotoxin MII[L15A] |
GCCSNPVCHLEHSNAC |
synthetic construct [Synthetic] |
Nicotinic acetylcholine receptor antagonist, Neuroactive, Ion channel inhibitory |
mouse CNS α-conotoxin MII binding site |
0.30 nM | Ki |
15044624 | - |
YES |
| 420542 | Rec_0433200 | TPRLPSSADVE |
TPRLPSSADVE |
Homo sapiens [Animal] |
T-cell antigenic, Immunomodulatory |
HLA-B*3501-restricted tyrosinase-specific T-cell clones |
- | TNF release assay |
14634146 | US 2006/0122119 A1 |
YES |
| 420543 | Rec_0433201 | LFRLKKWIRKVTRLFG |
LFRLKKWIRKVTRLFG |
synthetic construct [Synthetic] |
Antimicrobial, Antibacterial |
Escherichia coli ATCC 25922 |
11.03±0.46 | Radial diffusion assay (clear-zone readout) |
- | US 8076286 B2 |
YES |
| 420544 | Rec_0433202 | LFRLKKWIRKVTRLFG |
LFRLKKWIRKVTRLFG |
synthetic construct [Synthetic] |
Antimicrobial, Antibacterial |
Staphylococcus aureus ATCC 29213 |
8.59±0.13 | Radial diffusion assay (clear-zone readout) |
- | US 8076286 B2 |
YES |
| 420545 | Rec_0433203 | LFRLKKWIRKVTRLFG |
LFRLKKWIRKVTRLFG |
synthetic construct [Synthetic] |
Hemolytic |
human erythrocytes |
21.18±1.48 % | Hemolysis assay |
- | US 8076286 B2 |
YES |
| 420546 | Rec_0433204 | Pituitary adenylate cyclase-activating peptide-27 |
HSDGVFTDSYSRYRKQMAVKKYLATVL |
Danio rerio [Animal] |
Receptor agonist, Adenylyl cyclase activator |
Danio rerio PAC1 receptor |
- | adenylyl cyclase/cAMP signaling assay |
15713535 | - |
YES |
| 420547 | Rec_0433205 | Pituitary adenylate cyclase-activating peptide-27 |
HSDGVFTDSYSRYRKQMAVKKYLATVL |
Danio rerio [Animal] |
Receptor agonist, Adenylyl cyclase activator |
Danio rerio VPAC1 receptor |
- | adenylyl cyclase/cAMP signaling assay |
15713535 | - |
YES |
| 420548 | Rec_0433206 | Microcionamide A |
VCIIIIC |
Clathria (Thalysias) abietina [Animal] |
Cytotoxic, Anticancer |
SK-BR-3 human breast cancer cells |
98 nM | IC50 |
15176844 | - |
YES |
| 420549 | Rec_0433207 | Microcionamide A |
VCIIIIC |
Clathria (Thalysias) abietina [Animal] |
Cytotoxic, Anticancer |
MCF-7 human breast cancer cells |
125 nM | IC50 |
15176844 | - |
YES |
| 420550 | Rec_0433208 | Microcionamide A |
VCIIIIC |
Clathria (Thalysias) abietina [Animal] |
Antimicrobial, Antibacterial |
Mycobacterium tuberculosis H37Ra |
5.7 μM | MIC |
15176844 | - |
YES |
| 420551 | Rec_0433209 | Octapeptide OP (ODN11-18) |
RPGLLDLK |
- |
Neuropeptide, Intracellular calcium mobilization |
cultured rat astrocytes |
- | intracellular calcium mobilization assay |
9804683 | - |
YES |
| 420552 | Rec_0433210 | Bacteriocin Enterocin 1071 subunit beta [Q10D] |
GPGKWLPWLDPAYDFVTGLAKGIGKEGNKNKWKNV |
synthetic construct [Synthetic] |
Antimicrobial, Antibacterial, Bacteriocin |
Enterococcus faecalis NCDO 581 |
0.3±0.1 nM | MIC (1:1 with Enterocin 1071 alpha) |
17337546 | - |
YES |
| 420553 | Rec_0433211 | Bacteriocin Enterocin 1071 subunit beta [Q10D] |
GPGKWLPWLDPAYDFVTGLAKGIGKEGNKNKWKNV |
synthetic construct [Synthetic] |
Antimicrobial, Antibacterial, Bacteriocin |
Enterococcus faecalis LMGT-2333 |
0.3±0.1 nM | MIC (1:1 with Enterocin 1071 alpha) |
17337546 | - |
YES |
| 420554 | Rec_0433212 | P6V8-3NCSA1,5,7,8,10 (SEQ ID NO:35) |
AGRGARAAEAQRPSDKPRR |
synthetic construct [Synthetic] |
Receptor-binding, Anti-angiogenic |
Neuropilin-1 (NP-1) |
67.76 relative affinity (fold) | receptor-binding competition assay (relative affinity from IC50) |
- | US 20030186868 A1 |
YES |
| 420555 | Rec_0433213 | P6V8-3NCSA1,5,7,8,10 (SEQ ID NO:35) |
AGRGARAAEAQRPSDKPRR |
synthetic construct [Synthetic] |
Receptor-binding, Anti-angiogenic |
VEGFR-2/NP-1 receptor complex |
5.22 relative affinity (fold) | receptor-binding competition assay (relative affinity from IC50) |
- | US 20030186868 A1 |
YES |
| 420556 | Rec_0433214 | Neuromedin-U-23 |
SDEEVQVPGGVISNGYFLFRPRN |
Litoria caerulea [Animal] |
Neuropeptide, Hormone, Myotropic |
human urinary bladder muscle strips |
- | smooth muscle contraction assay |
10671478 | - |
YES |
| 420557 | Rec_0433215 | Thionin NsW1 |
KSCCKNTLGRNCYNTCRFMKKPRKTCSGLCGCKIS |
Nigella sativa [Plant] |
Antimicrobial, Antibacterial |
Staphylococcus aureus |
3.25 μM | IC50 |
- | - |
YES |
| 420558 | Rec_0433216 | Thionin NsW1 |
KSCCKNTLGRNCYNTCRFMKKPRKTCSGLCGCKIS |
Nigella sativa [Plant] |
Antimicrobial, Antibacterial |
Staphylococcus aureus |
6.5 μM | MIC |
- | - |
YES |
| 420559 | Rec_0433217 | Thionin NsW1 |
KSCCKNTLGRNCYNTCRFMKKPRKTCSGLCGCKIS |
Nigella sativa [Plant] |
Antimicrobial, Antibacterial |
Bacillus subtilis |
1.63 μM | IC50 |
- | - |
YES |
| 420560 | Rec_0433218 | Thionin NsW1 |
KSCCKNTLGRNCYNTCRFMKKPRKTCSGLCGCKIS |
Nigella sativa [Plant] |
Antimicrobial, Antibacterial |
Bacillus subtilis |
3.25 μM | MIC |
- | - |
YES |